Pancreatic Secretion

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• controlled by neural and hormonal signals

Triggers

• presence in duodenum of
  • acid
  • products of digestion
  • NOT triglycerides
• secretin
• cholecystokinin

Products

• alkaline secretion
  • 150ml/hr or 3500ml/day
• lipase
  • some secreted from glands near base of tongue
  • pancreatic lipase requires co-lipase to become active
• co-lipase
• trypsin
• chymotrpsin
• carboxypeptidases
• amylase

Actions

• triglyceride breakdown to form
  • free fatty acids
  • 2-monoglycerides

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